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By then she had been a professional football player for 6 months and practised several hours a day generic 50 mcg flonase with mastercard, including approx generic 50mcg flonase otc. In addition she had played 20 whole football games as a professional in the course of 6 months. Games as well as training were characterised by jumping/running with frequent starts and stops while bending and extending the knee, and there was pressure on the kneecap. It appeared that a year previously she had jumpers knee in the same place, which developed in connection with football playing in her leisure time as member of an ordinary football club. But there had been a continued tendency to pain in the knee after severe loads during training. Even though the stresses as a professional football player for 6 months were sufficient to develop jumpers knee, the football player previously, and without correlation with work, suffered from jumpers knee. This substantially increases her disposition to develop the disease again due to chronic degeneration of the tendon attachment. Nor are there any grounds for submitting the claim to the Occupational Diseases Committee. This is because it was not possible to recognise the disease, it not being likely beyond reasonable doubt that the disorder was caused, solely or mainly, by working as a football player. Medical glossary (jumpers knee) Latin/medical term English translation Anterior In front of Arthritis Inflammatory degeneration of one or several joints Arthrosis Degenerative arthritis Arthroscopy Scoping or looking into a joint Bursitis Inflammatory degeneration of a bursa Chondromalacia patella Softened cartilage behind the knee cap Femoral Of the femur Femoro-patellar pain Pain in the joint between kneecap (patella) and thigh bone (femur) syndrome Femur Thigh bone Lateral On the outer side Ligamentum cruciatum Cruciate ligament Ligamentum patellae The common tendon, which continues from the patella (knee cap) to the tibia (shin bone) 130 Meniscus lateralis External meniscus, half-moon-shaped cartilage disc between thigh bone and shin bone Meniscus medialis Internal meniscus, half-moon-shaped cartilage disc between thigh bone and shin bone M. Hand-arm vibration disorders (white finger, peripheral neuropathy, degenerative arthritis (C. Exposure requirements for recognition of degenerative arthritis (arthrosis) of wrist and elbow joint 1.

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Similar are Error accumulation and Accumulative waste theories; Error accumulation theory explains aging as the results from chance events that escape proofread ing mechanisms of genetic code [32] generic 50mcg flonase with mastercard, according to Accumulative waste theory the aging re sults from build-up of cell waste products in time because of defective repair-removal processes order 50 mcg flonase free shipping. Terman, [33] believes that the process of aging derives from imperfect clearance of oxidatively damaged, relatively indigestible material, the accumulation of which further hinders cellular catabolic and anabolic functions (e. It describes beneficial ac tions resulting from the response of an organism to a low-intensity stressor. It has been known since the 1930s that restricting calories while maintaining adequate amounts of other nutrients can extend the lifespan in laboratory animals. Additionally, the Disposable soma theory was proposed [36, 37], which postulated a special class of gene mutations with the following antagonistic pleiotropic effects: these hypotheti cal mutations save energy for reproduction (positive effect) by partially disabling molecular proofreading and other accuracy promoting devices in somatic cells (negative effect). The 336 Oxidative Stress and Chronic Degenerative Diseases - A Role for Antioxidants Evolutionary theory of aging is based on life history theory and is constituted of a set of ideas that themselves require further elaboration and validation [38]. Evidence implies that an important theme linking several different kinds of cellular damage is the consequence of exposure to reactive oxygen species [5, 39]. None of the theories explain the ag ing process, as it may be too complex to be covered by only one theory. Perhaps there is no single mechanism responsible for aging in all living organisms [42]. In essence, aging is progressive accumulation through life of many random molecular defects that build up within the cells and tissues. For this reason, only one magic bullet will never be able to prevent or reverse the complex and multicaus al process of aging. The Role of Oxidative Stress on the General Aging Process In order to understand strategies to reduce oxidative stress and aging, it is first important to briefly explain reasons for oxidative stress formation. The most important endogenous sources of oxi dants are mitochondrial electron transport chain and nitric oxide synthase reaction, and the non-mitochondrial soruces: Fenton reaction, reactions involving cytochromes P450 in micro somes, peroxisomal beta - oxidation and respiratory burst of phagocytic cells [6]. Free radi cal reactions have been implicated also as the consequence of exposure to many environmental pollutants, e.

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